UCL Nanomedicine Lab

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The logo_ucl is part of the UCL School of Life and Medical Sciences (incorporating UCL Medical School), one of the largest and most prestigious aggregations of academics in medical, brain, life and population health sciences.

The research activities are supported by partnerships with UCL NHS trusts, research councils, charities and industry.

UCL has also created the largest academic health science partnership in Europe known as UCL Partners, bringing UCL together with Great Ormond Street, Moorfields, Royal Free, and University College London Hospitals NHS Trusts. The aim is to enable new discoveries in basic science and their translation into treatments.

The Nanomedicine Lab at the UCL School of Pharmacy is one the first and premier research centres in Europe dedicated to nanomedicine and drug delivery. It has a long history in developing liposomes, colloidal nanoparticulates (polymeric microspheres, solid nanoparticles), natural and synthetic macromolecules (e.g. dendrimers) and novel nanomaterials (e.g. nanocarbons) as delivery systems of therapeutic and diagnostic agents. It has been awarded the following FP6 and FP7 European and International projects:

NINIVE; ANTICARB; SONODRUGS; NANONEUROHOP; NANORESISTENCE; RADDEL; BIS UK-Korea Global Partnership Fund amounting to a total of over €22.5M. Also as part of the EPSRC Centre for Doctoral Training (CDT) in Targeted Therapeutics, the Schools of Pharmacy at Nottingham and UCL have joined with AstraZeneca, GlaxoSmithKline, Pfizer, Alliance-Boots, Critical Pharmaceuticals, Quotient Clinical and Molecular Profiles to develop high level science and training that will span key sectors in the pharmaceutical sciences. Member of PCBNet – Stem Cells, Prion Proteins and Alzheimer’s Disease: A Prion Chemical Biology Network (EPSRC, BBSRC, MRC), a ground-breaking collaboration between academia and over 20 user organisations to aid research and knowledge-sharing at the chemical biology interface.

The Nanomedicine Lab has in-house comprehensive facilities that include: cell culture, gene expression in vitro and in vivo models, SEM, Optical microscope, cryo-TEM, Confocal laser scanning microscopy, NMR (500 MHz), Mass spectrometry (electrospray, LC-ESI-MS), Circular dichroism, Fluorescence (steady state and stopped-flow), Calorimetry (DSC and ITC), Biosensing (resonant mirror), nanoparticle characterisation (photon correlation spectrophotometry and ZetaSizer), HPLC, FPLC, tissue-culture hoods, Incubators, Centrifuges, Sonicators, Flow Cytometry, animal facility, IVIS fluorescence and bioluminescence imaging, SPECT/CT and PET/CT, Gamma counting, Liquid Scintillation Counting.

Key Personnel